If the screening test is negative, the Immunoblot will not be performed and you will not receive the bands with your results.Ī significant deviation from the normal range may require further evaluation by your physician. Doing so will increase the frequency of false positive results and may lead to misdiagnosis and improper treatment. CDC does not recommend skipping the first test and just doing the Immunoblot. The two steps of Lyme disease testing are designed to be done together. Results are considered positive only if the screening and the immunoblot are both positive. The second step uses a test called an immunoblot test. If the first step is positive or indeterminate (sometimes called "equivocal"), the second step should be performed. If this first step is negative, no further testing of the specimen is recommended. The first step uses a screening procedure. Both steps can be done using the same blood sample. The CDC currently recommends a two-step process when testing blood for evidence of antibodies against the Lyme disease bacteria. Immunoblot confirmation is recommended for positive results and is ONLY performed when the Lyme Disease Antibody screening is positive. If you don't get treatment, the infection can cause serious nerve or heart problems as well as a disabling type of arthritis (pain and swelling in one or more joints caused by inflammation).Ĭombination of IgM and IgM/IgG testing has the potential to provide the earliest and the broadest time window for serological detection. Lyme disease is an infection caused by the bite of an infected tick. Lyme Disease Antibodies (IgG, IgM) Immunoblot Confirmation is ONLY performed when the Lyme Disease Antibody screening is positive.Īids in the diagnosis of acute or chronic infection with the lyme disease agent. Immunoblot testing is appropriate for confirming a detected screening result. Immunoblot testing qualitatively examines with high specificity antibodies in a patient's specimen. The screening test is high sensitivity for antibody detection. Lyme disease is caused by a bacterium borrelia burgdorferi and is transmitted by ticks. Lyme Disease Antibody, Total EIA with Reflex to Antibodies IGG & IGM Western Blot
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